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About Us

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Accelerate Brain Cancer Cure is a nonprofit organization with a for-profit mindset. In 2001, after Dan Case was diagnosed with brain cancer, he devoted his energy and passion to lend hope for brain cancer patients by working to accelerate a cure and increase the number of potential therapies discovered and move them rapidly into the clinic for patients. Dan, together with his brother, Steve Case, their families, leading entrepreneurs, scientists and researchers, founded ABC2.


To hasten the discovery of a cure for brain cancer.


Through Research Award Grants, ABC2 provides innovative researchers with the support required to make critical translational breakthroughs.

ABC2 supports a Preclinical Screening Program at the Preston Robert Tisch Brain Tumor Center at Duke University which encourages the discovery and development of potential new and combination targeted therapies for patients at a rapidly accelerated pace.

As an independent, but collaborative force, ABC2 can identify specific areas for progress. ABC2 initiated and funds a Clinical Network, comprised of leading clinical investigators from four neuro-oncology centers (UCSF, UCLA, Preston Robert Tisch Brain Tumor Center at Duke University and M.D. Anderson ), to serve as a resource to accelerate the transition of therapies into clinical studies for patients.

ABC2 breaks-down the silos to convene medical/academia, industry and government in effort to increase strategic investments in brain cancer therapies and translational research. ABC2 uses its unique position to bring-together leaders in their respective fields to explore novel research that will speed new treatments to patients. These collaborations are focused on bringing new hope to brain cancer patients and uncovering the potential for treatments that might otherwise be overlooked.


Accelerate Brain Cancer Cure inspires new hope for a cure by using a results-driven business model to bring more treatments to patients, stimulate research & development and otherwise support the accelerated development of new therapies for brain cancer.


United States


1717 Rhode Island Avenue
Suite 700
Washington, DC 20036
Phone: (202) 419-3140
EIN: 52-2320756

Be An Investor

The Angel Fund

Your generous gift will buy one share of the ABC² Angel Investor Fund* (multiple shares are available) to fast-track cutting edge brain cancer research advancements. Accelerate Brain Cancer Cure was formed with the belief that the entrepreneurial model that has enabled so many technological innovations offers the best hope to fill the gap in funding. In the business world venture capitalists, sometimes called "angel investors,"...


Fund A Cure

One hour of research

Accelerate Brain Cancer Cure brings together researchers, clinicians, the biotech and pharmaceutical industry and government to fund research that translates promising laboratory successes into clinically meaningful improvements for patients. This approach is designed to provide innovative researchers with the support required to make critical translational breakthroughs. Accelerate Brain Cancer Cure fund proposals that will have an immediate impact, and we work actively and partner with...


Improve Treatments

Targeted therapy

There are new technologies through which we are developing an understanding of genes proteins and networks – offering the possibility to shift from a one-size fits all model. Your gift will help accelerate a cure for brain cancer through supporting pioneering innovation and technology to find the right therapy for the right patient at the right time. This approach will redefine the nature of the...


Build A Team

Convene researchers

Your gift will help pay the way for one researcher to attend the ABC2 Annual Scientific Meeting. Over the years, we have found this annual scientific meeting to be the most effective means by which to draw the field closer together and foster collaboration across institutional lines. The annual meeting emphasizes the importance of creating a supportive climate for scientific and medical research with a...


Break Down Silos

Network collaboration

You gift will help foster collaboration across institutional lines and hasten a cure for brain cancer. To accelerate the transition of therapies into clinical studies for patients, ABC² has initiated a strategic collaboration, the ABC² Clinical Network. It is composed of four leading neuro-oncology centers and clinical investigators who work together to: provide guidance and counsel to the sponsors of drug therapies (particularly in the...


Drive Innovation

Develop new therapies

In an effort to quicken the evaluation of therapeutic candidates for possible advancement to the clinic for brain cancer patients, ABC2 partnered with the Preston Robert Tisch Brain Center at Duke University to form the Preclinical Screening Program. Your gift will support a critical link with the biopharmaceutical industry and academia and help fill a void in the drug development arena by providing a venue...


Make A Difference

Brain cancer research

Your gift will provide much needed hope to patients with brain cancer. You will move this underserved field forward to make a difference by bringing an innovative approach to finding therapies for this devastating disease.


Develop Leaders

Research award

Your investment will help attract the best and brightest researchers to the field of brain cancer. Young Investigator Awards encourage and invest in physician-scientists who are building their careers in translational medicine. The awards provide support for a three-year period in neuro-oncology and address key scientific and medical challenges in the development of effective brain cancer therapies.


Enable Research

Laboratory supplies

When you purchase lab supplies, you are providing researchers the support and supplies they need to make groundbreaking translational research advancements. Your gift will help facilitate the efforts of hard-working and dedicated researchers.